Cancer Biology

Cancer biology encompasses the application of systems biology approaches to cancer research, in order to study the disease as a complex adaptive system with emerging properties at multiple biological scales. More explicitly, because cancer spans multiple biological, spatial and temporal scales, communication and feedback mechanisms across the scales create a highly complex dynamic system.

Cancer biology therefore adopts a holistic view of cancer aimed at integrating its many biological scales, including genetics, signaling networks, epigenetics, cellular behavior, histology, (pre)clinical manifestations and epidemiology. Basic researchers and clinicians have progressively recognized the complexity of cancer and of its interaction with the micro- and macro-environment, since putting together the components to provide a cohesive view of the disease has been challenging and hampered progress. Most recent research are going on Cancer Genetics, Carcinogenesis, DNA damage and repair, apoptosis, angiogenesis, and metastasis, Tumor microenvironment, Molecular mechanisms of Cancer Pathogenesis, Cancer stem cells, Discovery of tumor suppressor genes, Aberrant signaling pathways in tumor cells, Roles of ubiquitination pathways in cancer, Molecular cancer epidemiology and Cancer detection and therapy.

  • Cancer Genetics
  • Carcinogenesis,DNA damage and repair
  • Apoptosis, angiogenesis, metastasis
  • Tumor microenvironment
  • Molecular mechanisms of cancer pathogenesis
  • Cancer stem cells
  • Discovery of tumor suppressor genes
  • Aberrant signaling pathways in tumor cells
  • Roles of ubiquitination pathways in cancer
  • Molecular cancer epidemiology
  • Cancer detection and therapy

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